TB vaccine closer
PUBLISHED: 15:51 13 November 2007 | UPDATED: 08:17 28 March 2014
Vaccination to control bovine tuberculosis could be a step closer with the development of a test which can distinguish between vaccinated and infected animals.
This would involve using the same vaccination used to immunise humans against the disease, BCG.
However, BCG-vaccinated cattle test positive using the tuberculin skin
test. Before a bovine TB vaccination strategy can be implemented, a
method of distinguishing between vaccinated and infected animals has to
The diagnostic test developed relies on the information that immune
cells of cattle previously infected with TB contain more of the protein
gamma interferon than those vaccinated for TB.
The test can provide
same day, on farm diagnosis of TB and identify which are vaccinated and
which are infected.